PENGARUH PEMBERIAN AIR REBUSAN MAHKOTA DEWA (Phaleria macrocarpa (Scheff) Boerl) TERHADAP KADAR ASAM URAT DARAH PADA WANITA MENOPAUSE
Abstract
Water decoction of Mahkota Dewa (Phaleria macrocarpa (Scheff) Boerl)’s effect on Blood Uric Acid Levels in Menopaused Women
Â
Uric acid is the final result of purine metabolism in the body, which excreted through urine. In gout conditions, there is uric acid crystals deposit in joints. In the women's uric acid levels did not increase until menopause because estrogen helps to increase spending uric acid in the kidneys by reducing the amount of uric acid reabsorption. Phaleria macrocarpa (Scheff) Boerl is a plant that has medicinal properties to treat gout because Phaleria macrocarpa (Scheff) Boerl contains flavonoids that can lower uric acid by the mechanism of resistance to the activity of xanthine oxidase on purine bases so that it will reduce production of uric acid. The purpose of this study was to determine the effect of giving Phaleria macrocarpa (Scheff) Boerl’s decoction water on uric acid’s level in postmenopausal women in RW 01 Kelurahan Kebonsari Sukun Malang. This research is Pre Experiment with one group pre-post test design. Using 24 postmenopausal women who suffer from uric acid with total sampling technique. Test data analysis using the Wilcoxon Signed Rank Test on the significant level α = 0.05. The results showed 87.5% of respondents had decreased levels of uric acid and 12.5% of respondents did not experience changes in uric acid’s level or are likely to remain. Results of analysis of test data with Wilcoxon Signed Rank Test Zhitung obtained (-4.02) < ZTable (1,96). It’s means there is influence of Phaleria macrocarpa (Scheff) Boerl’s decoction water to reduction of uric acid levels in postmenopausal women. Referring to these results it is expected that Phaleria macrocarpa (Scheff) Boerl can be used as therapy in the treatment of gout.
Â
Keywords : Water decoction of Mahkota Dewa, Levels of Uric Acid, Female MenopauseReferences
Arini S, Nurmawan D, Alfiani F, Hertiani T. 2003. Daya Antioksidan dan Kadar Flavonoid Hasil Ekstraksi Etanol-air Daging Buah Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl.). Buletin Penalaran Mahasiswa UGM
Baziat, Ali. 2003. Menopause dan Andropause. Jakarta. YBPSP.
Dewani. 2006. 33 Ramuan Penakluk Asam Urat. Jakarta: Agro Media Pustaka.
Dini, Kasdu. 2002. Kiat Sehat dan Bahagia di Usia Menopause. Jakarta. Puspa Suara.
Harmanto, Ning. 2005. Menggempur Asam Urat dan Rematik dengan Mahkota Dewa. Jakarta: Agro Media Pustaka.
Harmanto, Ning. 2005. Menaklukkan Penyakit Bersama mahkota Dewa. Jakarta. Agromedia Pustaka,
Hidayat. 2007. Metode Penelitian Kebidanan dan Tehnik Analisis Data. Jakarta: Salemba Medika.
Jones-Derek Llewelyn. 2001. Dasar-dasar Obstetri dan Ginekologi. Jakarta. Hipokratis.
Junaedi, dr.Iskandar.2008.Rematik dan Asam Urat.Jakarta:PT.Buana Ilmu Populer.
Kertia, Nyoman. 2009. Asam Urat Benarkah Hanya Menyerang Laki –Laki. Yogyakarta: Bentang Pustaka.
Muhammad, As’adi. 2010. Waspadai Asam Urat. Yogyakarta: Diva Press.
Murray, Robert K dkk. 2003. Biokimia Harper. Jakarta: EGC.
Saraswati, Sylvia. 2009. Diet Sehat: untuk Penyakit Asam Urat, Diabetes, Hipertensi, dan Stroke. Yogyakarta: A+Plus Books.
Spencer, Rebecca Fox dan Pam Brown. 2006. Menopause. Jakarta: Erlangga.
Tagliaferri, Mary. 2006. The New Menopause Book: Ihwal yang Perlu Anda Ketahui Menopause. Jakarta. PT. Indeks Kelompok Gramedia.
Tersono, Lukas. 2008. Tanaman Obat dan Jus untuk Mengatasi Penyakit Jantung, Hipertensi, Kolesterol, dan Stroke. Jakarta: Agro Media Pustaka.
Varney, Helen et al. 2006. Buku Ajar Asuhan Kebidanan Volume 1. Jakarta: EGC.
Wibowo, Suryo. 2009. 100 Questons & Answers Asam Urat. Jakarta : PT Elex Media Komputindo.
Wijayakusuma, Hembing. 2006. Atasi Rematik dan Asam Urat Ala Hembing. Jakarta : Puspa Swara.
Winarto, W.P. 2005. Mahkota Dewa: Budidaya & Pemanfaatan untuk Obat. Jakarta: Penebar Swadaya.
Yatim, Faisal. 2001. Haid Tidak Lancar dan Menopause. Jakarta. Pustaka Populer Obor.
