Web Platform for Automated Detection of Abnormal Red Blood Cells Using Computer Vision

Authors

DOI:

https://doi.org/10.25047/ijhitech.v3i2.6718

Keywords:

blood cell classification, red blood cells, deep learning, MobileNetV2, web-based platform

Abstract

Accurate identification of red blood cell (RBC) morphological abnormalities is essential for anemia screening and hematological assessment; however, manual microscopic examination remains time-consuming, subjective, and highly dependent on expert availability. While recent deep learning studies have demonstrated promising accuracy in RBC classification, many focus primarily on model performance without addressing practical deployment constraints or system-level integration for routine laboratory use. In this study, a web-based prototype system for automated RBC abnormality classification is proposed using a lightweight MobileNetV2 architecture. The dataset consisted of 1,320 microscopic blood smear images collected from Klinik & Laboratorium Parahita in Jember and Surabaya, covering six RBC categories with balanced class distribution. All images were anonymized and verified by a certified clinical pathologist prior to use. The model was trained using transfer learning and evaluated on a held-out test set to assess generalization performance. The proposed model achieved a test accuracy of 89.77%, with consistent precision, recall, and F1-score across classes, indicating reliable multi-class classification performance. Analysis of misclassified samples revealed uncertainty primarily between morphologically similar RBC types, reflected by lower confidence scores. These results demonstrate that lightweight deep learning models can provide effective and efficient support for RBC morphology analysis when integrated into an accessible web-based system. The proposed approach contributes a deployment-oriented diagnostic support tool that has the potential to assist laboratory professionals by improving screening efficiency and consistency while preserving clinical oversight.

References

[1] E. Humphry and C. E. Armstrong, “Physiology of red and white blood cells,” Anaesthesia & Intensive Care Medicine, vol. 23, no. 2, pp. 118–122, 2022.

[2] J. Ford, “Red blood cell morphology,” Int J Lab Hematol, vol. 35, no. 5, pp. 351–357, 2013, doi: 10.1111/ijlh.12082.

[3] R. Gupta, T. A. Kakani, J. Vedula, M. Mohammed, K. Hudani, and N. Yuvaraj, “Advancing Clinical Decision-Making using Artificial Intelligence and Machine Learning for Accurate Disease Diagnosis,” in 2025 6th International Conference on Intelligent Communication Technologies and Virtual Mobile Networks (ICICV), 2025, pp. 164–169.

[4] A. M. Williams, N. Ansai, N. Ahluwalia, and D. T. Nguyen, “Anemia Prevalence: United States, August 2021-August 2023,” 2024.

[5] G. M. Brittenham et al., “Biology of Anemia: A Public Health Perspective,” J Nutr, vol. 153, pp. S7–S28, 2023, doi: https://doi.org/10.1016/j.tjnut.2023.07.018.

[6] S. Safiri et al., “Burden of anemia and its underlying causes in 204 countries and territories, 1990–2019: results from the Global Burden of Disease Study 2019,” J Hematol Oncol, vol. 14, no. 1, p. 185, 2021.

[7] J. Sun, H. Wu, M. Zhao, C. G. Magnussen, and B. Xi, “Prevalence and changes of anemia among young children and women in 47 low-and middle-income countries, 2000-2018,” EClinicalMedicine, vol. 41, 2021.

[8] S. Choudhary et al., “Advancing blood cell detection and classification: performance evaluation of modern deep learning models,” BMC Med Inform Decis Mak, vol. 25, no. 1, p. 207, 2025, doi: 10.1186/s12911-025-03027-2.

[9] A. Abougarair et al., “Blood Cells Cancer Detection Based on Deep Learning,” Journal of Advances in Artificial Intelligence, vol. 2, pp. 108–121, Sep. 2024, doi: 10.18178/JAAI.2024.2.1.108-121.

[10] J. Jeevan, K. M. Karun, A. Puranik, C. Deepa, L. Mk, and M. Barvaliya, “Prevalence of anemia in India: a systematic review, meta-analysis and geospatial analysis,” BMC Public Health, vol. 25, no. 1, p. 1270, 2025.

[11] I. Kumar and J. Rawat, “Segmentation and classification of white blood SMEAR images using modified CNN architecture,” Discover Applied Sciences, vol. 6, no. 11, p. 587, 2024, doi: 10.1007/s42452-024-06139-y.

[12] M. Sandler, A. Howard, M. Zhu, A. Zhmoginov, and L.-C. Chen, “MobileNetV2: Inverted Residuals and Linear Bottlenecks,” 2019. [Online]. Available: https://arxiv.org/abs/1801.04381

[13] R. U. Khan, S. Almakdi, M. Alshehri, A. U. Haq, A. Ullah, and R. Kumar, “An intelligent neural network model to detect red blood cells for various blood structure classification in microscopic medical images,” Heliyon, vol. 10, p. e26149, 2024, doi: 10.1016/j.heliyon. 2024.e26149.

[14] S. Choudhary et al., “Advancing blood cell detection and classification: performance evaluation of modern deep learning models,” BMC Med Inform Decis Mak, vol. 25, p. 207, 2025, doi: 10.1186/s12911-025-03027-2.

[15] X. Z. Wang, G. J. Pan, Z. G. Hu, and A. R. Ge, “A two stage blood cell detection and classification algorithm based on improved YOLOv7 and EfficientNetv2,” Sci Rep, vol. 15, p. 8427, 2025, doi: 10.1038/s41598-025-91720-7.

[16] R. Patel and A. Chaware, “Quantizing MobileNet Models for Classification Problem,” 2021 8th International Conference on Computing for Sustainable Global Development (INDIACom), pp. 348–351, 2021, doi: 10.1109/INDIACom51348.2021.00060.

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Published

2025-12-24

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How to Cite

Web Platform for Automated Detection of Abnormal Red Blood Cells Using Computer Vision. (2025). International Journal of Healthcare and Information Technology, 3(2), 109–119. https://doi.org/10.25047/ijhitech.v3i2.6718

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